Anti-Aging Peptides
Longevity peptides researched for cellular health, telomere support, and healthy aging.
About Anti-Aging Peptides
Anti-aging peptides represent a cutting-edge area of longevity research. These compounds are studied for their potential to support cellular health, protect telomeres, enhance mitochondrial function, and promote healthy aging. Notable examples include Epithalon (a telomerase activator), various bioregulator peptides developed by Vladimir Khavinson, and NAD+ precursor peptides. Research suggests these peptides may influence gene expression patterns associated with aging.
All Anti-Aging Peptides (7)
DSIP
Clinical TrialsAlso: Delta Sleep Inducing Peptide, Delta Sleep-Inducing Peptide
A neuropeptide that promotes deep delta wave sleep. First isolated from rabbit brains in 1977. Used for sleep optimization and stress reduction.
Humanin
PreclinicalAlso: HN, HNG (S14G-humanin)
A mitochondria-derived peptide discovered for its neuroprotective effects against Alzheimer's-related toxicity. Being studied for aging and metabolic benefits.
NAD+ Precursors
Clinical TrialsAlso: NMN, NR
While not peptides, NAD+ precursors are frequently discussed alongside peptides in longevity circles. They boost cellular NAD+ levels, supporting energy metabolism and sirtuin activity.
SS-31
FDA ApprovedAlso: Elamipretide, Bendavia
A mitochondria-targeted peptide that improves cellular energy production. FDA approved for Barth syndrome (September 2025) as FORZINITY, the first approved mitochondria-targeted therapeutic.
Glutathione
Clinical TrialsAlso: L-Glutathione, GSH
The body's master antioxidant - a tripeptide composed of glutamate, cysteine, and glycine. Found in every cell at concentrations similar to glucose (5mM). Essential for detoxification, immune function, and cellular protection against oxidative stress.
FOXO4-DRI
PreclinicalAlso: FOX04-DRI, FOXO4 D-Retro-Inverso
A senolytic peptide designed to selectively eliminate senescent 'zombie' cells by disrupting the FOXO4-p53 interaction. Shows promise for restoring tissue function in aging, including kidney health restoration.
Vesilute
PreclinicalAlso: ED Dipeptide, Glu-Asp
A synthetic dipeptide (Glu-Asp) bioregulator from the Khavinson peptide family, studied for urinary tract and prostate support. Research suggests it may help with bladder function and prostate microcirculation. Part of the tissue-specific bioregulatory compounds developed over 40+ years of research.
Frequently Asked Questions About Anti-Aging Peptides
What are anti-aging peptides?
Anti-aging peptides are compounds researched for their potential to slow biological aging, support cellular health, and promote longevity. They work through various mechanisms including telomerase activation, gene expression modulation, and mitochondrial support.
How does Epithalon work?
Epithalon is a synthetic tetrapeptide that has been shown to activate telomerase, the enzyme responsible for maintaining telomere length. Telomere shortening is associated with cellular aging, and Epithalon's ability to activate telomerase may support cellular longevity.
What are bioregulator peptides?
Bioregulator peptides, developed by Professor Vladimir Khavinson, are short peptides that target specific organs and tissues. They're theorized to help restore optimal gene expression patterns that may decline with age, supporting organ-specific function.