Immune Peptides
Peptides researched for immune modulation, antimicrobial properties, and immune support.
About Immune Peptides
Immune peptides encompass compounds researched for their effects on immune function, including immune modulators, antimicrobial peptides, and immunostimulants. Thymosin Alpha-1 is FDA-approved in many countries for immune support. Other notable immune peptides include LL-37 (an antimicrobial peptide), KPV (anti-inflammatory), and various thymic peptides. These compounds are studied for their potential to modulate immune responses and support the body's natural defenses.
All Immune Peptides (7)
LL-37
Clinical TrialsAlso: Cathelicidin, CAP18
A naturally occurring antimicrobial peptide and the only human cathelicidin. Part of the innate immune system with broad-spectrum antimicrobial activity.
Thymosin Alpha-1
Clinical TrialsAlso: Ta1, Zadaxin
A naturally occurring thymic peptide that enhances immune function. Approved in over 35 countries for hepatitis B/C and as an immune adjuvant.
KPV
PreclinicalAlso: Lys-Pro-Val, Alpha-MSH fragment
A tripeptide derived from alpha-melanocyte stimulating hormone (α-MSH). Known for potent anti-inflammatory effects, particularly in the gut.
VIP
Clinical TrialsAlso: Vasoactive Intestinal Peptide, Aviptadil
A naturally occurring peptide with immunomodulatory and anti-inflammatory effects. Being studied for ARDS, pulmonary hypertension, and autoimmune conditions.
Enfuvirtide
FDA ApprovedAlso: Fuzeon, T-20
A peptide HIV fusion inhibitor that blocks viral entry into cells. First approved drug in the fusion inhibitor class.
PNC27
PreclinicalAlso: PNC-27, p53-HDM2 Disruptor Peptide
A chimeric anti-cancer peptide containing p53 residues 12-26 linked to a membrane-penetrating sequence. Selectively kills cancer cells by binding to HDM-2 expressed on cancer cell membranes, inducing membrane pore formation and necrosis while leaving normal cells unaffected.
Thymogen
Clinical TrialsAlso: EW Dipeptide, Glu-Trp
A synthetic dipeptide (Glu-Trp) bioregulator derived from Thymalin, a thymus extract. One of Professor Khavinson's key immunomodulatory peptides, shown to stimulate T-lymphocyte development and normalize immune function. Has been used clinically in Russia for immune support.
Frequently Asked Questions About Immune Peptides
What are immune peptides?
Immune peptides are compounds that modulate immune function. They include immunostimulants like Thymosin Alpha-1, antimicrobial peptides like LL-37, and anti-inflammatory peptides. They work through various mechanisms to support immune system function.
Is Thymosin Alpha-1 FDA approved?
Thymosin Alpha-1 is approved in over 30 countries for various immune-related conditions including hepatitis B and C. While not FDA approved in the US, it has extensive clinical research supporting its immune-modulating properties.
How do antimicrobial peptides work?
Antimicrobial peptides like LL-37 are part of the innate immune system. They can directly kill bacteria, viruses, and fungi by disrupting their cell membranes. They also modulate immune responses and promote wound healing.