Pegvisomant Alternatives

Explore peptides similar to Pegvisomant. Compare mechanisms, effects, and find the best alternative for your research.

Original

Pegvisomant

Hormonal

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A GH receptor antagonist that blocks growth hormone action. Used for acromegaly when surgery and somatostatin analogs fail to normalize IGF-1.

Similar Peptides

Gonadorelin

Hormonal

FDA

A synthetic version of gonadotropin-releasing hormone. Used diagnostically and therapeutically for various reproductive and hormonal conditions.

Lanreotide

Hormonal

FDA

A long-acting somatostatin analog similar to octreotide. FDA approved for acromegaly and gastroenteropancreatic neuroendocrine tumors.

Macimorelin

Hormonal

FDA

An oral ghrelin mimetic used to diagnose adult growth hormone deficiency. The first FDA-approved oral GH stimulation test.

Oxytocin

Hormonal

FDA

A naturally occurring peptide hormone crucial for social bonding, childbirth, and lactation. Being studied for autism, anxiety, and social disorders.

Leuprolide

Hormonal

FDA

A GnRH agonist that suppresses testosterone and estrogen production. FDA approved for prostate cancer, endometriosis, uterine fibroids, and precocious puberty.

Desmopressin

Hormonal

FDA

A synthetic analog of vasopressin (ADH) used for diabetes insipidus, bedwetting, and bleeding disorders. Does not cause vasoconstriction like natural vasopressin.

All Hormonal Peptides

Kisspeptin

A neuropeptide that plays a critical role in initiating puberty and regulating the reproductive hormone axis. Being studied for fertility and hormonal disorders.

MOTS-c

A mitochondria-derived peptide that regulates metabolic homeostasis. Discovered in 2015, it's being studied for its effects on insulin sensitivity, exercise capacity, and aging.

Oxytocin

FDA Approved

A naturally occurring peptide hormone crucial for social bonding, childbirth, and lactation. Being studied for autism, anxiety, and social disorders.

Gonadorelin

FDA Approved

A synthetic version of gonadotropin-releasing hormone. Used diagnostically and therapeutically for various reproductive and hormonal conditions.

Leuprolide

FDA Approved

A GnRH agonist that suppresses testosterone and estrogen production. FDA approved for prostate cancer, endometriosis, uterine fibroids, and precocious puberty.

Desmopressin

FDA Approved

A synthetic analog of vasopressin (ADH) used for diabetes insipidus, bedwetting, and bleeding disorders. Does not cause vasoconstriction like natural vasopressin.

Octreotide

FDA Approved

A synthetic somatostatin analog that inhibits multiple hormones. Used for acromegaly, carcinoid tumors, and various GI conditions.

Lanreotide

FDA Approved

A long-acting somatostatin analog similar to octreotide. FDA approved for acromegaly and gastroenteropancreatic neuroendocrine tumors.

Quick Comparison

PeptideCategoryFDA StatusAction
PegvisomantHormonal✓ ApprovedOriginal
GonadorelinHormonal✓ ApprovedCompare →
LanreotideHormonal✓ ApprovedCompare →
MacimorelinHormonal✓ ApprovedCompare →
OxytocinHormonal✓ ApprovedCompare →