LL-37 Alternatives

Explore peptides similar to LL-37. Compare mechanisms, effects, and find the best alternative for your research.

Original

LL-37

Immune

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A naturally occurring antimicrobial peptide and the only human cathelicidin. Part of the innate immune system with broad-spectrum antimicrobial activity.

Similar Peptides

Thymosin Alpha-1

Immune

A naturally occurring thymic peptide that enhances immune function. Approved in over 35 countries for hepatitis B/C and as an immune adjuvant.

KPV

Immune

A tripeptide derived from alpha-melanocyte stimulating hormone (α-MSH). Known for potent anti-inflammatory effects, particularly in the gut.

VIP

Immune

A naturally occurring peptide with immunomodulatory and anti-inflammatory effects. Being studied for ARDS, pulmonary hypertension, and autoimmune conditions.

Enfuvirtide

Immune

FDA

A peptide HIV fusion inhibitor that blocks viral entry into cells. First approved drug in the fusion inhibitor class.

TB-500

Healing

A synthetic 17-amino acid fragment of Thymosin Beta-4 (TB-4). NOT the same as TB-4 - TB-500 has a longer half-life (~2-4 days vs ~2 hours) and is the active region responsible for tissue repair and cell migration. Note: Many vendors mislabel TB-4 as 'TB-500' in premixed products.

Matrixyl 3000

Skin & Hair

An advanced version of Matrixyl combining two peptides for enhanced anti-aging effects. Targets both collagen production and inflammation.

All Immune Peptides

Thymosin Alpha-1

A naturally occurring thymic peptide that enhances immune function. Approved in over 35 countries for hepatitis B/C and as an immune adjuvant.

KPV

A tripeptide derived from alpha-melanocyte stimulating hormone (α-MSH). Known for potent anti-inflammatory effects, particularly in the gut.

VIP

A naturally occurring peptide with immunomodulatory and anti-inflammatory effects. Being studied for ARDS, pulmonary hypertension, and autoimmune conditions.

Enfuvirtide

FDA Approved

A peptide HIV fusion inhibitor that blocks viral entry into cells. First approved drug in the fusion inhibitor class.

Quick Comparison

PeptideCategoryFDA StatusAction
LL-37ImmuneNot ApprovedOriginal
Thymosin Alpha-1ImmuneNot ApprovedCompare →
KPVImmuneNot ApprovedCompare →
VIPImmuneNot ApprovedCompare →
EnfuvirtideImmune✓ ApprovedCompare →