A counter-regulatory hormone to insulin. FDA approved for severe hypoglycemia treatment and diagnostic procedures.

Is Glucagon FDA approved?

Yes, Glucagon is FDA approved. FDA Approved - Hypoglycemia and diagnostic

What are the side effects of Glucagon?

Reported side effects of Glucagon include: Nausea (up to 35%), Vomiting, Headache, Hypertension, Tachycardia, Allergic reactions, Rebound hypoglycemia, CONTRAINDICATED with pheochromocytoma, FDA approved.

What is the typical dosing for Glucagon?

Emergency dosing. Common doses observed in research: 1 mg IM/SC/IV for hypoglycemia, 3 mg intranasal (Baqsimi). Duration: Single dose emergency use. Administration: Injection, intranasal, or auto-injector.

Hormonal

Glucagon

Also known as: GlucaGen, Baqsimi

FDA Approved

Popular For

Hypoglycemia emergency, blood sugar rescue

Key Facts: Glucagon

Category: Hormonal
FDA Status: FDA Approved
Clinical Status: FDA Approved - Hypoglycemia and diagnostic
Administration: Injection, intranasal, or auto-injector
Typical Dose: Limited community data available
Frequency: See research protocols
Evidence Level: FDA Approved
Duration: Single dose emergency use

Also Known As

GlucaGen, Baqsimi

Mechanism of Action

Glucagon binds to glucagon receptors in the liver, activating glycogenolysis and gluconeogenesis to raise blood glucose. Also relaxes smooth muscle in the GI tract for diagnostic imaging.

Research Summary

Life-saving treatment for severe hypoglycemia since the 1960s. Newer formulations include nasal spray (Baqsimi) and stable liquid (Gvoke). Essential emergency medication for insulin users.

Clinical Status:FDA Approved - Hypoglycemia and diagnostic

Trial Progress:FDA Approved

Pre

III

FDA

Dosing Information

FDA Approved·Human clinical trials completed, FDA approved

Typical DosingⓘDoses commonly used by people in practice, based on community reports and anecdotal experience.

Community experience

Common Dose

Limited community data available

Range

See research dosing

Frequency

See research protocols

Research DosingⓘDoses from published scientific studies and clinical trials. May include human or animal research.

Scientific studies

Emergency dosing

Doses from Studies

1 mg IM/SC/IV for hypoglycemia

FDA Approved Labeling - Prescribed dose ↗

3 mg intranasal (Baqsimi)

FDA Approved Labeling - Prescribed dose ↗

Duration

Single dose emergency use

Administration

Injection, intranasal, or auto-injector

Timing & Administration

Best Time to Take

Morning

Follow specific protocol

Food Recommendation

Take on empty stomach

Why This Timing?

Metabolic peptides often work best when taken in the morning to support daytime energy expenditure.

Possible Side Effects

Not everyone experiences these effects. Individual responses vary based on dosage, duration, and personal factors.

●Nausea (up to 35%)
●Vomiting
●Headache
●Hypertension
●Tachycardia
●Allergic reactions
●Rebound hypoglycemia
●CONTRAINDICATED with pheochromocytoma
●FDA approved

References

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