BPC-157 vs GHK-Cu
Comprehensive side-by-side comparison of mechanisms, dosing, side effects, and research
Also: Body Protection Compound-157, Pentadecapeptide BPC 157
A synthetic peptide derived from a protein found in human gastric juice. Known for its remarkable tissue healing properties across multiple body systems.
Also: Copper Peptide, Glycyl-L-histidyl-L-lysine copper
A naturally occurring copper-binding peptide found in human plasma, saliva, and urine. Widely used in skincare for its wound healing and anti-aging properties.
Key Comparison Insights
- BPC-157 is categorized as Healing, while GHK-Cu is Skin & Hair.
- BPC-157 has stronger research evidence (Animal Studies) compared to GHK-Cu (Limited Research).
- These peptides are often used together in healing protocols for synergistic effects.
Detailed Comparison
| Attribute | BPC-157 | GHK-Cu |
|---|---|---|
| Category | Healing | Skin & Hair |
| FDA Status | Not FDA Approved | Not FDA Approved |
| Clinical Status | Pre I II III IV FDA | Pre I II III IV FDA |
| Mechanism of Action | BPC-157 modulates the nitric oxide system, promotes angiogenesis (new blood vessel formation), and upregulates growth hormone receptors. It also interacts with the dopaminergic system and has been shown to accelerate tendon-to-bone healing by promoting collagen synthesis. | GHK-Cu stimulates collagen and elastin synthesis, promotes glycosaminoglycan production, supports blood vessel growth, and has antioxidant and anti-inflammatory properties. It remodels damaged tissue and activates wound-healing genes. |
| Common Dosing | 250-500 mcg twice daily 1-2x daily | 1-2 mg daily (injection) or topical Once daily |
| Administration | Subcutaneous injection near injury site, or systemic | Subcutaneous injection or topical application |
| Typical Duration | 4-12 weeks in most research protocols | Varies by application |
| Best Time to Take | Morning and evening (or near injury site timing) | Evening (for skin/recovery) |
Possible Side Effects May vary by individual |
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| Research Summary | Extensive preclinical studies demonstrate efficacy in healing tendons, ligaments, muscles, and the GI tract. Animal studies show acceleration of wound healing, protection against NSAID-induced gut damage, and neuroprotective effects. Limited human clinical trials exist. | Studies demonstrate increased collagen synthesis, improved skin elasticity, reduced fine lines, and accelerated wound healing. Research shows it can reset gene expression to a healthier state and may have systemic anti-aging effects beyond skin. |
Frequently Asked Questions: BPC-157 vs GHK-Cu
What is the difference between BPC-157 and GHK-Cu?
BPC-157 is a healing peptide that a synthetic peptide derived from a protein found in human gastric juice. known for its remarkable tissue healing properties across multiple body systems. GHK-Cu is a skin & hair peptide that a naturally occurring copper-binding peptide found in human plasma, saliva, and urine. widely used in skincare for its wound healing and anti-aging properties. The main differences lie in their mechanisms of action and clinical applications.
Which is better, BPC-157 or GHK-Cu?
Neither is universally "better" - the choice depends on your specific goals. BPC-157 is typically used for healing purposes, while GHK-Cu is used for skin & hair. Always consult with a healthcare provider to determine which may be appropriate for your situation.
Can BPC-157 and GHK-Cu be used together?
Some peptide protocols combine multiple compounds for synergistic effects. However, using BPC-157 and GHK-Cu together should only be considered under medical supervision, as both compounds have their own side effect profiles and potential interactions. Research on their combined use may be limited.
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Educational Information Only
This comparison of BPC-157 and GHK-Cu is for educational purposes only. Neither this comparison nor any information on this site constitutes medical advice. Always consult with qualified healthcare providers before making decisions about peptides or other substances.