Vesugen
Also known as: Lys-Glu-Asp, KED
Popular For
Vascular health, blood vessel support, circulation
Key Facts: Vesugen
- Category
- Bioregulators
- FDA Status
- Not FDA Approved
- Clinical Status
- Preclinical research, approved in Russia as supplement
- Administration
- Oral capsules or sublingual
- Typical Dose
- 10-20 mg daily
- Frequency
- Once or twice daily
- Evidence Level
- Preclinical
- Duration
- 10-30 day cycles
Mechanism of Action
Vesugen stimulates proliferation-associated protein Ki-67 in vascular endothelial cells, counteracting age-related decline. It promotes tissue restoration and normalization of vessel function through direct gene regulatory effects on vascular cells.
Research Summary
Studies in tissue-specific cell cultures from young and old animals showed Vesugen stimulated Ki-67 expression that decreases during aging. Research demonstrates age-associated protective properties in vascular endothelial cell cultures.
Dosing Information
Note: Animal study doses may not translate directly to humans.
Typical Dosingⓘ
Community experience
10-20 mg daily
10-20 mg daily
Once or twice daily
Vascular bioregulator. Part of Khavinson peptide system for cardiovascular support.
Research Dosingⓘ
Scientific studies
Doses from bioregulator supplement protocols
Doses from Studies
10-20 mg daily
Duration
10-30 day cycles
Administration
Oral capsules or sublingual
Timing & Administration
Best Time to Take
Morning on empty stomach
Once or twice daily
Food Recommendation
Take on empty stomach
Why This Timing?
Peptide bioregulators typically taken fasted for optimal absorption
Possible Side Effects
Not everyone experiences these effects. Individual responses vary based on dosage, duration, and personal factors.
- ●Generally well-tolerated
- ●Limited safety data outside Russia
- ●Not FDA approved
References
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