MK-677 Alternatives

Explore peptides similar to MK-677. Compare mechanisms, effects, and find the best alternative for your research.

Original

MK-677

Growth Hormone

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An orally active growth hormone secretagogue that mimics ghrelin. Not a peptide technically, but frequently discussed alongside GH peptides due to similar effects.

Similar Peptides

Ipamorelin

Growth Hormone

A selective growth hormone secretagogue that stimulates GH release without significantly affecting cortisol or prolactin. Considered one of the safest GHRPs.

CJC-1295

Growth Hormone

A synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates GH release from the pituitary. Often combined with a GHRP like Ipamorelin for synergistic effects.

Tesamorelin

Growth Hormone

FDA

An FDA-approved GHRH analog used to reduce excess abdominal fat in HIV-infected patients with lipodystrophy. One of the few peptides with FDA approval.

GHRP-6

Growth Hormone

One of the first synthetic GH secretagogues developed. Strongly stimulates GH release and significantly increases appetite through ghrelin receptor activation.

GHRP-2

Growth Hormone

A synthetic hexapeptide that potently stimulates GH release. More potent than GHRP-6 with less appetite stimulation, but still elevates cortisol and prolactin.

Sermorelin

Growth Hormone

A truncated analog of natural GHRH containing the first 29 amino acids. Previously FDA-approved for pediatric GH deficiency, now used off-label for adult hormone optimization.

All Growth Hormone Peptides

Ipamorelin

A selective growth hormone secretagogue that stimulates GH release without significantly affecting cortisol or prolactin. Considered one of the safest GHRPs.

CJC-1295

A synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates GH release from the pituitary. Often combined with a GHRP like Ipamorelin for synergistic effects.

Tesamorelin

FDA Approved

An FDA-approved GHRH analog used to reduce excess abdominal fat in HIV-infected patients with lipodystrophy. One of the few peptides with FDA approval.

GHRP-6

One of the first synthetic GH secretagogues developed. Strongly stimulates GH release and significantly increases appetite through ghrelin receptor activation.

GHRP-2

A synthetic hexapeptide that potently stimulates GH release. More potent than GHRP-6 with less appetite stimulation, but still elevates cortisol and prolactin.

Sermorelin

A truncated analog of natural GHRH containing the first 29 amino acids. Previously FDA-approved for pediatric GH deficiency, now used off-label for adult hormone optimization.

Hexarelin

A synthetic hexapeptide GH secretagogue with the strongest GH-releasing effect among GHRPs. Also has notable cardioprotective properties independent of GH release.

CJC-1295 DAC

A long-acting GHRH analog with Drug Affinity Complex for extended half-life. Provides sustained GH elevation for days with single injection.

Quick Comparison

PeptideCategoryFDA StatusAction
MK-677Growth HormoneNot ApprovedOriginal
IpamorelinGrowth HormoneNot ApprovedCompare →
CJC-1295Growth HormoneNot ApprovedCompare →
TesamorelinGrowth Hormone✓ ApprovedCompare →
GHRP-6Growth HormoneNot ApprovedCompare →