Semax vs Cerebrolysin
Comprehensive side-by-side comparison of mechanisms, dosing, side effects, and research
Also: SEMAX, Heptapeptide SEMAX
A synthetic peptide derived from ACTH (4-10) fragment with added Pro-Gly-Pro sequence. Approved in Russia for stroke and cognitive enhancement. Known for nootropic and neuroprotective effects.
Also: FPE 1070
A mixture of low-molecular-weight neuropeptides derived from pig brain. Approved in many countries for stroke, traumatic brain injury, and dementia.
Key Comparison Insights
- Both peptides belong to the Cognitive category, suggesting similar primary applications.
Detailed Comparison
| Attribute | Semax | Cerebrolysin |
|---|---|---|
| Category | Cognitive | Cognitive |
| FDA Status | Not FDA Approved | Not FDA Approved |
| Clinical Status | Pre I II III IV FDA | Pre I II III IV FDA |
| Mechanism of Action | Semax increases BDNF and NGF expression, modulates dopamine and serotonin systems, and has anti-inflammatory effects in the brain. It enhances neuroplasticity and protects neurons from oxidative stress and excitotoxicity. | Cerebrolysin contains neurotrophic factors that mimic BDNF, NGF, and CNTF activity. It enhances neuroplasticity, protects neurons from excitotoxicity, promotes neurogenesis, and improves synaptic function. |
| Common Dosing | 200-600 mcg intranasal daily 1-3x daily, intranasal | 5-10 ml IV/IM daily for 10-20 days Daily during treatment cycles |
| Administration | Intranasal spray (most common) | Intravenous or intramuscular injection |
| Typical Duration | 10-30 days typical | 10-20 day cycles |
| Best Time to Take | Morning or early afternoon | Morning |
Possible Side Effects May vary by individual |
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| Research Summary | Russian research shows cognitive enhancement, improved memory and attention, and benefits for stroke recovery. Studies demonstrate increased BDNF levels and neuroprotective effects. Used clinically in Russia for stroke, TBI, and cognitive disorders. | Approved in over 40 countries for neurological conditions. Studies show benefits in stroke recovery, Alzheimer's disease, and TBI. Large clinical trials demonstrate improved cognitive function and activities of daily living. |
Frequently Asked Questions: Semax vs Cerebrolysin
What is the difference between Semax and Cerebrolysin?
Semax is a cognitive peptide that a synthetic peptide derived from acth (4-10) fragment with added pro-gly-pro sequence. approved in russia for stroke and cognitive enhancement. known for nootropic and neuroprotective effects. Cerebrolysin is a cognitive peptide that a mixture of low-molecular-weight neuropeptides derived from pig brain. approved in many countries for stroke, traumatic brain injury, and dementia. The main differences lie in their mechanisms of action and clinical applications.
Which is better, Semax or Cerebrolysin?
Neither is universally "better" - the choice depends on your specific goals. Semax is typically used for cognitive purposes, while Cerebrolysin is used for cognitive. Always consult with a healthcare provider to determine which may be appropriate for your situation.
Can Semax and Cerebrolysin be used together?
Some peptide protocols combine multiple compounds for synergistic effects. However, using Semax and Cerebrolysin together should only be considered under medical supervision, as both compounds have their own side effect profiles and potential interactions. Research on their combined use may be limited.
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Educational Information Only
This comparison of Semax and Cerebrolysin is for educational purposes only. Neither this comparison nor any information on this site constitutes medical advice. Always consult with qualified healthcare providers before making decisions about peptides or other substances.