Epithalon vs Humanin
Comprehensive side-by-side comparison of mechanisms, dosing, side effects, and research
Also: Epitalon, Epithalone
A tetrapeptide studied for its effects on telomerase activation and potential anti-aging properties. Based on research by Professor Vladimir Khavinson.
Also: HN, HNG (S14G-humanin)
A mitochondria-derived peptide discovered for its neuroprotective effects against Alzheimer's-related toxicity. Being studied for aging and metabolic benefits.
Key Comparison Insights
- Epithalon is categorized as Bioregulators, while Humanin is Anti-Aging.
- Epithalon has stronger research evidence (Human Trials) compared to Humanin (Animal Studies).
Detailed Comparison
| Attribute | Epithalon | Humanin |
|---|---|---|
| Category | Bioregulators | Anti-Aging |
| FDA Status | Not FDA Approved | Not FDA Approved |
| Clinical Status | Pre I II III IV FDA | Pre I II III IV FDA |
| Mechanism of Action | Epithalon stimulates telomerase production, potentially slowing or reversing telomere shortening. It may also regulate melatonin production by the pineal gland and has been shown to influence gene expression related to aging. | Humanin acts through multiple pathways including STAT3 signaling, binding to IGFBP-3, and activating the FPRL1 receptor. It protects neurons from apoptosis, improves insulin sensitivity, and has anti-inflammatory effects. |
| Common Dosing | 5-10 mg daily for 10-20 days Once daily in cycles | 5-10 mg weekly divided into 2-3 injections 2-3x weekly (e.g., Monday, Wednesday, Friday) |
| Administration | Subcutaneous or intramuscular injection | Injection (route varies) |
| Typical Duration | 10-20 day cycles | Variable |
| Best Time to Take | Before bed | Morning |
Possible Side Effects May vary by individual |
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| Research Summary | Russian studies show increased telomerase activity and extended lifespan in animal models. Human studies suggest improved sleep, reduced cortisol, and potential immune benefits. Research quality and Western replication remains limited. | Research shows protection against amyloid-beta toxicity in Alzheimer's models. Studies demonstrate improved insulin sensitivity, reduced atherosclerosis in animal models, and potential anti-aging effects. Human studies are limited. |
Frequently Asked Questions: Epithalon vs Humanin
What is the difference between Epithalon and Humanin?
Epithalon is a bioregulators peptide that a tetrapeptide studied for its effects on telomerase activation and potential anti-aging properties. based on research by professor vladimir khavinson. Humanin is a anti-aging peptide that a mitochondria-derived peptide discovered for its neuroprotective effects against alzheimer's-related toxicity. being studied for aging and metabolic benefits. The main differences lie in their mechanisms of action and clinical applications.
Which is better, Epithalon or Humanin?
Neither is universally "better" - the choice depends on your specific goals. Epithalon is typically used for bioregulators purposes, while Humanin is used for anti-aging. Always consult with a healthcare provider to determine which may be appropriate for your situation.
Can Epithalon and Humanin be used together?
Some peptide protocols combine multiple compounds for synergistic effects. However, using Epithalon and Humanin together should only be considered under medical supervision, as both compounds have their own side effect profiles and potential interactions. Research on their combined use may be limited.
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Educational Information Only
This comparison of Epithalon and Humanin is for educational purposes only. Neither this comparison nor any information on this site constitutes medical advice. Always consult with qualified healthcare providers before making decisions about peptides or other substances.