Comparison

Pinealon vs Epithalon

Comprehensive side-by-side comparison of mechanisms, dosing, side effects, and research

Pinealon

Also: EDR, Glu-Asp-Arg

Preclinical

A synthetic tripeptide bioregulator targeting brain tissue. Part of Khavinson's peptide research, designed to support cognitive function and neuroprotection.

BioregulatorsAnimal Studies
Epithalon

Also: Epitalon, Epithalone

Clinical Trials

A tetrapeptide studied for its effects on telomerase activation and potential anti-aging properties. Based on research by Professor Vladimir Khavinson.

BioregulatorsHuman Trials

Key Comparison Insights

  • Both peptides belong to the Bioregulators category, suggesting similar primary applications.
  • Epithalon has stronger research evidence (Human Trials) compared to Pinealon (Animal Studies).

Detailed Comparison

AttributePinealonEpithalon
CategoryBioregulatorsBioregulators
FDA StatusNot FDA ApprovedNot FDA Approved
Clinical Status
Pre
I
II
III
IV
FDA
Pre
I
II
III
IV
FDA
Mechanism of ActionPinealon regulates gene expression in brain cells, particularly those involved in neuronal survival and function. It modulates melatonin synthesis, supports circadian rhythm, and has antioxidant effects in neural tissue.Epithalon stimulates telomerase production, potentially slowing or reversing telomere shortening. It may also regulate melatonin production by the pineal gland and has been shown to influence gene expression related to aging.
Common Dosing
10-20 mg daily
Once daily, typically evening
5-10 mg daily for 10-20 days
Once daily in cycles
AdministrationOral or sublingualSubcutaneous or intramuscular injection
Typical Duration10-30 day courses10-20 day cycles
Best Time to TakeEvening or before bedBefore bed
Possible Side Effects
May vary by individual
  • Generally well-tolerated
  • Headache
  • Nausea
  • Dizziness
  • Vivid dreams
  • +2 more
  • Generally well-tolerated
  • Injection site reactions
  • Mild headache (transient)
  • Sleep disturbances
  • Risk of immunogenicity
  • +1 more
Research SummaryRussian studies show neuroprotective effects and cognitive improvement in aging. Research demonstrates protection against hypoxia and oxidative stress. Used in combination with other bioregulator peptides.Russian studies show increased telomerase activity and extended lifespan in animal models. Human studies suggest improved sleep, reduced cortisol, and potential immune benefits. Research quality and Western replication remains limited.

Frequently Asked Questions: Pinealon vs Epithalon

What is the difference between Pinealon and Epithalon?

Pinealon is a bioregulators peptide that a synthetic tripeptide bioregulator targeting brain tissue. part of khavinson's peptide research, designed to support cognitive function and neuroprotection. Epithalon is a bioregulators peptide that a tetrapeptide studied for its effects on telomerase activation and potential anti-aging properties. based on research by professor vladimir khavinson. The main differences lie in their mechanisms of action and clinical applications.

Which is better, Pinealon or Epithalon?

Neither is universally "better" - the choice depends on your specific goals. Pinealon is typically used for bioregulators purposes, while Epithalon is used for bioregulators. Always consult with a healthcare provider to determine which may be appropriate for your situation.

Can Pinealon and Epithalon be used together?

Some peptide protocols combine multiple compounds for synergistic effects. However, using Pinealon and Epithalon together should only be considered under medical supervision, as both compounds have their own side effect profiles and potential interactions. Research on their combined use may be limited.

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Educational Information Only

This comparison of Pinealon and Epithalon is for educational purposes only. Neither this comparison nor any information on this site constitutes medical advice. Always consult with qualified healthcare providers before making decisions about peptides or other substances.