BPC-157 vs Ipamorelin
Comprehensive side-by-side comparison of mechanisms, dosing, side effects, and research
Also: Body Protection Compound-157, Pentadecapeptide BPC 157
A synthetic peptide derived from a protein found in human gastric juice. Known for its remarkable tissue healing properties across multiple body systems.
Also: IPAM, NNC 26-0161
A selective growth hormone secretagogue that stimulates GH release without significantly affecting cortisol or prolactin. Considered one of the safest GHRPs.
Key Comparison Insights
- BPC-157 is categorized as Healing, while Ipamorelin is Growth Hormone.
- Ipamorelin has stronger research evidence (Human Trials) compared to BPC-157 (Animal Studies).
Detailed Comparison
| Attribute | BPC-157 | Ipamorelin |
|---|---|---|
| Category | Healing | Growth Hormone |
| FDA Status | Not FDA Approved | Not FDA Approved |
| Clinical Status | Pre I II III IV FDA | Pre I II III IV FDA |
| Mechanism of Action | BPC-157 modulates the nitric oxide system, promotes angiogenesis (new blood vessel formation), and upregulates growth hormone receptors. It also interacts with the dopaminergic system and has been shown to accelerate tendon-to-bone healing by promoting collagen synthesis. | Ipamorelin binds to ghrelin receptors (GHSR) in the pituitary gland, triggering growth hormone release. Unlike other GHRPs, it does not stimulate significant ACTH, cortisol, prolactin, or aldosterone release, making it highly selective for GH. |
| Common Dosing | 250-500 mcg twice daily 1-2x daily | 200-300 mcg 2-3x daily 2-3x daily |
| Administration | Subcutaneous injection near injury site, or systemic | Subcutaneous injection |
| Typical Duration | 4-12 weeks in most research protocols | 8-12 weeks typical |
| Best Time to Take | Morning and evening (or near injury site timing) | Before bed or morning (fasted) |
Possible Side Effects May vary by individual |
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| Research Summary | Extensive preclinical studies demonstrate efficacy in healing tendons, ligaments, muscles, and the GI tract. Animal studies show acceleration of wound healing, protection against NSAID-induced gut damage, and neuroprotective effects. Limited human clinical trials exist. | Clinical studies show dose-dependent GH release with minimal side effects. Research demonstrates improved bone density in postmenopausal women and potential benefits for muscle mass and recovery. Has been studied for post-surgical recovery. |
Frequently Asked Questions: BPC-157 vs Ipamorelin
What is the difference between BPC-157 and Ipamorelin?
BPC-157 is a healing peptide that a synthetic peptide derived from a protein found in human gastric juice. known for its remarkable tissue healing properties across multiple body systems. Ipamorelin is a growth hormone peptide that a selective growth hormone secretagogue that stimulates gh release without significantly affecting cortisol or prolactin. considered one of the safest ghrps. The main differences lie in their mechanisms of action and clinical applications.
Which is better, BPC-157 or Ipamorelin?
Neither is universally "better" - the choice depends on your specific goals. BPC-157 is typically used for healing purposes, while Ipamorelin is used for growth hormone. Always consult with a healthcare provider to determine which may be appropriate for your situation.
Can BPC-157 and Ipamorelin be used together?
Some peptide protocols combine multiple compounds for synergistic effects. However, using BPC-157 and Ipamorelin together should only be considered under medical supervision, as both compounds have their own side effect profiles and potential interactions. Research on their combined use may be limited.
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Educational Information Only
This comparison of BPC-157 and Ipamorelin is for educational purposes only. Neither this comparison nor any information on this site constitutes medical advice. Always consult with qualified healthcare providers before making decisions about peptides or other substances.