How to Use SS-31
Complete guide to SS-31 dosing, administration, timing, and protocol recommendations.
Quick Overview
A mitochondria-targeted peptide that improves cellular energy production. FDA approved for Barth syndrome (September 2025) as FORZINITY, the first approved mitochondria-targeted therapeutic.
Dosing Guidelines
Common Dose
40 mg subcutaneous daily
Frequency
Once daily
Dose Range
40 mg daily
Note: FDA approved as FORZINITY for Barth syndrome. Subcutaneous injection for patients weighing at least 30 kg.
Administration Method
Subcutaneous injection or IV infusion
Best Time to Take
Morning
SS-31 (Elamipretide) targets mitochondria. Morning use supports daytime energy production.
Protocol Duration
Variable by condition
Possible Side Effects
Not everyone experiences these. Individual responses vary.
- •Injection site reactions (very common - 80%)
- •Headache
- •Dizziness
- •Nausea
- •May trigger histamine release - use caution with MCAS or histamine sensitivity
Frequently Asked Questions
What is the recommended dose for SS-31?
40 mg subcutaneous daily
How do you administer SS-31?
Subcutaneous injection or IV infusion
When is the best time to take SS-31?
Morning
How long should you use SS-31?
Variable by condition
This information is for educational purposes only. Always consult with a healthcare professional before using any peptide. Dosing information is based on research literature and community reports, not medical advice.