How to Use Setmelanotide
Complete guide to Setmelanotide dosing, administration, timing, and protocol recommendations.
Quick Overview
An MC4R agonist for rare genetic obesity disorders. FDA approved for specific gene mutations causing obesity.
Dosing Guidelines
Common Dose
2-3 mg daily
Frequency
Once daily
Dose Range
1-3 mg daily
Note: FDA-approved for specific genetic obesities (POMC, PCSK1, LEPR deficiency). Prescription only.
Administration Method
Subcutaneous injection daily
Best Time to Take
Before bed or morning (fasted)
GH-related peptides work best on an empty stomach to maximize growth hormone release.
Protocol Duration
Long-term / chronic use
Possible Side Effects
Not everyone experiences these. Individual responses vary.
- •Skin hyperpigmentation (67-83%)
- •Injection site reactions
- •Nausea
- •Spontaneous erections in males
- •Priapism risk
Frequently Asked Questions
What is the recommended dose for Setmelanotide?
2-3 mg daily
How do you administer Setmelanotide?
Subcutaneous injection daily
When is the best time to take Setmelanotide?
Before bed or morning (fasted)
How long should you use Setmelanotide?
Long-term / chronic use
This information is for educational purposes only. Always consult with a healthcare professional before using any peptide. Dosing information is based on research literature and community reports, not medical advice.