Semaglutide Oral Alternatives

Explore peptides similar to Semaglutide Oral. Compare mechanisms, effects, and find the best alternative for your research.

Original

Semaglutide Oral

Weight Loss

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The oral formulation of semaglutide using SNAC absorption enhancer. First oral GLP-1 receptor agonist FDA approved.

Similar Peptides

Semaglutide

Weight Loss

FDA

A GLP-1 receptor agonist FDA-approved for type 2 diabetes and chronic weight management. One of the most effective pharmaceutical weight loss interventions available.

Tirzepatide

Weight Loss

FDA

A dual GIP/GLP-1 receptor agonist representing the next generation of incretin-based therapies. Shows superior weight loss compared to semaglutide in head-to-head trials.

Liraglutide

Weight Loss

FDA

An FDA-approved GLP-1 receptor agonist for type 2 diabetes and chronic weight management. The predecessor to semaglutide with daily dosing.

Dulaglutide

Weight Loss

FDA

An FDA-approved weekly GLP-1 receptor agonist for type 2 diabetes. Fused to an Fc antibody fragment for extended duration of action.

Exenatide

Weight Loss

FDA

The first GLP-1 receptor agonist approved for diabetes. Derived from Gila monster saliva. Available in twice-daily and weekly formulations.

Setmelanotide

Weight Loss

FDA

An MC4R agonist for rare genetic obesity disorders. FDA approved for specific gene mutations causing obesity.

All Weight Loss Peptides

Semaglutide

FDA Approved

A GLP-1 receptor agonist FDA-approved for type 2 diabetes and chronic weight management. One of the most effective pharmaceutical weight loss interventions available.

Tirzepatide

FDA Approved

A dual GIP/GLP-1 receptor agonist representing the next generation of incretin-based therapies. Shows superior weight loss compared to semaglutide in head-to-head trials.

AOD-9604

A modified fragment of human growth hormone (amino acids 177-191) studied for fat metabolism effects without the broader hormonal effects of full GH.

Retatrutide

A triple agonist targeting GLP-1, GIP, and glucagon receptors. Represents the next evolution beyond dual agonists like tirzepatide, showing unprecedented weight loss in trials.

HGH Fragment 176-191

The lipolytic fragment of human growth hormone. Contains the fat-burning portion of HGH without effects on blood sugar or cell proliferation.

Liraglutide

FDA Approved

An FDA-approved GLP-1 receptor agonist for type 2 diabetes and chronic weight management. The predecessor to semaglutide with daily dosing.

Dulaglutide

FDA Approved

An FDA-approved weekly GLP-1 receptor agonist for type 2 diabetes. Fused to an Fc antibody fragment for extended duration of action.

Exenatide

FDA Approved

The first GLP-1 receptor agonist approved for diabetes. Derived from Gila monster saliva. Available in twice-daily and weekly formulations.

Quick Comparison

PeptideCategoryFDA StatusAction
Semaglutide OralWeight Loss✓ ApprovedOriginal
SemaglutideWeight Loss✓ ApprovedCompare →
TirzepatideWeight Loss✓ ApprovedCompare →
LiraglutideWeight Loss✓ ApprovedCompare →
DulaglutideWeight Loss✓ ApprovedCompare →