How to Use Humanin
Complete guide to Humanin dosing, administration, timing, and protocol recommendations.
Quick Overview
Humanin is a 24-amino-acid peptide encoded inside mitochondrial DNA (in the 16S rRNA gene), discovered in 2001 and named for its ability to protect human neurons from Alzheimer-related cell death. It was the first member of the mitochondrial-derived peptide family and is studied mainly for neuroprotection, cell survival, and metabolic and age-related disease. The honest status: it has the deepest preclinical evidence base of any mitochondrial peptide, but human therapeutic trials are essentially absent.
Dosing Guidelines
Common Dose
5-10 mg weekly divided into 2-3 injections
Frequency
2-3x weekly (e.g., Monday, Wednesday, Friday)
Dose Range
5-10 mg per week
Note: Subcutaneous injection to abdomen or thigh. Cycle 2-4 weeks on, 2-4 weeks off. Often stacked with MOTS-c and NAD+ for mitochondrial support. Store lyophilized at 0-5°C; reconstituted solution stable 5 days at 4°C or freeze for longer storage.
Administration Method
Injection (route varies)
Best Time to Take
Morning
Humanin is a mitochondrial peptide. Morning use supports daytime cellular energy demands.
Protocol Duration
Variable
Possible Side Effects
Not everyone experiences these. Individual responses vary.
- •Generally well-tolerated (preclinical)
- •Mild injection site reactions
- •Potential pro-tumoral effects
- •May affect glucose metabolism
- •No human clinical trial data
Frequently Asked Questions
What is the recommended dose for Humanin?
5-10 mg weekly divided into 2-3 injections
How do you administer Humanin?
Injection (route varies)
When is the best time to take Humanin?
Morning
How long should you use Humanin?
Variable
This information is for educational purposes only. Always consult with a healthcare professional before using any peptide. Dosing information is based on research literature and community reports, not medical advice.