Livagen vs Ovagen
Comprehensive side-by-side comparison of mechanisms, dosing, side effects, and research
Also: Lys-Glu-Asp-Ala, KEDA
A tetrapeptide bioregulator (Lys-Glu-Asp-Ala) developed by Khavinson that modulates chromatin structure and gene expression. Research shows it can decondense heterochromatin and activate ribosomal genes, potentially restoring more youthful gene expression patterns in aging cells.
Also: Glu-Asp-Leu, EDL
A tripeptide bioregulator (Glu-Asp-Leu) targeting liver and gastrointestinal tissue. Derived from liver tissue extracts, Ovagen modulates gene expression related to detoxification, antioxidant defense, and hepatocellular repair.
Key Comparison Insights
- Both peptides belong to the Bioregulators category, suggesting similar primary applications.
Detailed Comparison
| Attribute | Livagen | Ovagen |
|---|---|---|
| Category | Bioregulators | Bioregulators |
| FDA Status | Not FDA Approved | Not FDA Approved |
| Clinical Status | Pre I II III IV FDA | Pre I II III IV FDA |
| Mechanism of Action | Livagen penetrates the cell nucleus and directly influences DNA transcription by decondensing chromatin structure. It activates ribosomal genes, modulates heterochromatin organization, and affects enkephalin-degrading enzyme activity. This allows previously silenced genes to become accessible for transcription, potentially restoring cellular function. | Ovagen interacts with intracellular regulatory systems, modulating chromatin structure and transcription-factor accessibility. In hepatic and GI systems, it influences markers of cellular proliferation, extracellular matrix organization, and mucosal signaling pathways. Supports protein synthesis and antioxidant defense mechanisms. |
| Common Dosing | 10-20 mg daily Once or twice daily | 10-20 mg daily Once or twice daily |
| Administration | Oral capsules or sublingual | Oral capsules or sublingual |
| Typical Duration | 10-30 day cycles | 10-30 day cycles |
| Best Time to Take | Morning on empty stomach | Morning on empty stomach |
Possible Side Effects May vary by individual |
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| Research Summary | Studies in elderly subjects (75-88 years) showed Livagen activated ribosomal genes and induced decondensation of pericentromeric heterochromatin in lymphocytes. Research also demonstrated effects on the endogenous opioid system and immune cell function. Part of Khavinson's peptide bioregulator research spanning 40+ years. | Research focuses on hepatoprotective and GI mucosal support properties. Studies show modulation of gene expression patterns in liver tissue models. Part of the Khavinson peptide bioregulator family with tissue-specific regulatory effects. |
Frequently Asked Questions: Livagen vs Ovagen
What is the difference between Livagen and Ovagen?
Livagen is a bioregulators peptide that a tetrapeptide bioregulator (lys-glu-asp-ala) developed by khavinson that modulates chromatin structure and gene expression. research shows it can decondense heterochromatin and activate ribosomal genes, potentially restoring more youthful gene expression patterns in aging cells. Ovagen is a bioregulators peptide that a tripeptide bioregulator (glu-asp-leu) targeting liver and gastrointestinal tissue. derived from liver tissue extracts, ovagen modulates gene expression related to detoxification, antioxidant defense, and hepatocellular repair. The main differences lie in their mechanisms of action and clinical applications.
Which is better, Livagen or Ovagen?
Neither is universally "better" - the choice depends on your specific goals. Livagen is typically used for bioregulators purposes, while Ovagen is used for bioregulators. Always consult with a healthcare provider to determine which may be appropriate for your situation.
Can Livagen and Ovagen be used together?
Some peptide protocols combine multiple compounds for synergistic effects. However, using Livagen and Ovagen together should only be considered under medical supervision, as both compounds have their own side effect profiles and potential interactions. Research on their combined use may be limited.
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Educational Information Only
This comparison of Livagen and Ovagen is for educational purposes only. Neither this comparison nor any information on this site constitutes medical advice. Always consult with qualified healthcare providers before making decisions about peptides or other substances.