GHRP-2 vs Hexarelin
Comprehensive side-by-side comparison of mechanisms, dosing, side effects, and research
Also: Growth Hormone Releasing Peptide 2, Pralmorelin
A synthetic hexapeptide that potently stimulates GH release. More potent than GHRP-6 with less appetite stimulation, but still elevates cortisol and prolactin.
Also: Examorelin, HEX
A synthetic hexapeptide GH secretagogue with the strongest GH-releasing effect among GHRPs. Also has notable cardioprotective properties independent of GH release.
Key Comparison Insights
- Both peptides belong to the Growth Hormone category, suggesting similar primary applications.
Detailed Comparison
| Attribute | GHRP-2 | Hexarelin |
|---|---|---|
| Category | Growth Hormone | Growth Hormone |
| FDA Status | Not FDA Approved | Not FDA Approved |
| Clinical Status | Pre I II III IV FDA | Pre I II III IV FDA |
| Mechanism of Action | GHRP-2 acts on ghrelin receptors to stimulate GH release from the pituitary. It has the strongest GH-releasing effect among GHRPs but also causes more cortisol and prolactin release than ipamorelin. Less appetite stimulation than GHRP-6. | Hexarelin activates ghrelin receptors (GHSR-1a) causing potent GH release. Uniquely, it also binds to CD36 receptors in cardiac tissue, providing cardioprotective effects independent of GH. Causes significant cortisol and prolactin elevation. |
| Common Dosing | 100-300 mcg 2-3x daily 2-3x daily | 100-200 mcg 2-3x daily 2-3x daily |
| Administration | Subcutaneous injection | Subcutaneous injection |
| Typical Duration | 8-12 weeks | 4-8 weeks (desensitization occurs) |
| Best Time to Take | Before bed or morning (fasted) | Morning and before bed (fasted) |
Possible Side Effects May vary by individual |
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| Research Summary | Studies show it produces the highest GH release among common GHRPs. Research demonstrates reliable diagnostic use for GH deficiency testing. Animal studies show improved muscle mass and recovery. | Studies show the highest GH release among GHRPs but with desensitization over time. Cardiac research demonstrates protection against ischemia and improved heart function. Used in GH deficiency diagnosis due to reliable GH stimulation. |
Frequently Asked Questions: GHRP-2 vs Hexarelin
What is the difference between GHRP-2 and Hexarelin?
GHRP-2 is a growth hormone peptide that a synthetic hexapeptide that potently stimulates gh release. more potent than ghrp-6 with less appetite stimulation, but still elevates cortisol and prolactin. Hexarelin is a growth hormone peptide that a synthetic hexapeptide gh secretagogue with the strongest gh-releasing effect among ghrps. also has notable cardioprotective properties independent of gh release. The main differences lie in their mechanisms of action and clinical applications.
Which is better, GHRP-2 or Hexarelin?
Neither is universally "better" - the choice depends on your specific goals. GHRP-2 is typically used for growth hormone purposes, while Hexarelin is used for growth hormone. Always consult with a healthcare provider to determine which may be appropriate for your situation.
Can GHRP-2 and Hexarelin be used together?
Some peptide protocols combine multiple compounds for synergistic effects. However, using GHRP-2 and Hexarelin together should only be considered under medical supervision, as both compounds have their own side effect profiles and potential interactions. Research on their combined use may be limited.
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Educational Information Only
This comparison of GHRP-2 and Hexarelin is for educational purposes only. Neither this comparison nor any information on this site constitutes medical advice. Always consult with qualified healthcare providers before making decisions about peptides or other substances.