Comparison

GHK-Cu vs Copper Peptide AHK-Cu

Comprehensive side-by-side comparison of mechanisms, dosing, side effects, and research

GHK-Cu

Also: Copper Peptide, Glycyl-L-histidyl-L-lysine copper

Research

A naturally occurring copper-binding peptide found in human plasma, saliva, and urine. Widely used in skincare for its wound healing and anti-aging properties.

Skin & HairLimited Research
Copper Peptide AHK-Cu

Also: Tripeptide-3, Ala-His-Lys Copper

Research

A copper-binding tripeptide primarily used for hair growth stimulation. Shows promise for both hair loss prevention and scalp health.

Skin & HairLimited Research

Key Comparison Insights

  • Both peptides belong to the Skin & Hair category, suggesting similar primary applications.

Detailed Comparison

AttributeGHK-CuCopper Peptide AHK-Cu
CategorySkin & HairSkin & Hair
FDA StatusNot FDA ApprovedNot FDA Approved
Clinical Status
Pre
I
II
III
IV
FDA
Pre
I
II
III
IV
FDA
Mechanism of ActionGHK-Cu stimulates collagen and elastin synthesis, promotes glycosaminoglycan production, supports blood vessel growth, and has antioxidant and anti-inflammatory properties. It remodels damaged tissue and activates wound-healing genes.AHK-Cu binds copper and delivers it to hair follicles where it supports various enzymatic processes. It stimulates hair follicle cells, extends the growth phase of hair, and has wound-healing properties on the scalp.
Common Dosing
1-2 mg daily (injection) or topical
Once daily
Limited community data available
See research protocols
AdministrationSubcutaneous injection or topical applicationTopical (scalp serums, solutions)
Typical DurationVaries by application3-6 months for visible results
Best Time to TakeEvening (for skin/recovery)Morning or as directed
Possible Side Effects
May vary by individual
  • Generally well-tolerated
  • Topical: mild skin irritation, redness, or tingling
  • Injectable: injection site reactions
  • May trigger histamine release - use caution with MCAS or histamine sensitivity
  • Risk of copper toxicity with excessive use
  • +2 more
  • Generally well-tolerated
  • Skin irritation
  • Allergic reactions (rare)
  • Risk of copper toxicity if combined with copper sources
  • Contraindicated with Wilson's disease
Research SummaryStudies demonstrate increased collagen synthesis, improved skin elasticity, reduced fine lines, and accelerated wound healing. Research shows it can reset gene expression to a healthier state and may have systemic anti-aging effects beyond skin.Studies show increased hair count and thickness. Research demonstrates activation of hair follicle stem cells. Often combined with other hair growth peptides for synergistic effects.

Frequently Asked Questions: GHK-Cu vs Copper Peptide AHK-Cu

What is the difference between GHK-Cu and Copper Peptide AHK-Cu?

GHK-Cu is a skin & hair peptide that a naturally occurring copper-binding peptide found in human plasma, saliva, and urine. widely used in skincare for its wound healing and anti-aging properties. Copper Peptide AHK-Cu is a skin & hair peptide that a copper-binding tripeptide primarily used for hair growth stimulation. shows promise for both hair loss prevention and scalp health. The main differences lie in their mechanisms of action and clinical applications.

Which is better, GHK-Cu or Copper Peptide AHK-Cu?

Neither is universally "better" - the choice depends on your specific goals. GHK-Cu is typically used for skin & hair purposes, while Copper Peptide AHK-Cu is used for skin & hair. Always consult with a healthcare provider to determine which may be appropriate for your situation.

Can GHK-Cu and Copper Peptide AHK-Cu be used together?

Some peptide protocols combine multiple compounds for synergistic effects. However, using GHK-Cu and Copper Peptide AHK-Cu together should only be considered under medical supervision, as both compounds have their own side effect profiles and potential interactions. Research on their combined use may be limited.

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Educational Information Only

This comparison of GHK-Cu and Copper Peptide AHK-Cu is for educational purposes only. Neither this comparison nor any information on this site constitutes medical advice. Always consult with qualified healthcare providers before making decisions about peptides or other substances.