How to Use Thymosin Beta-4

Complete guide to Thymosin Beta-4 dosing, administration, timing, and protocol recommendations.

Quick Overview

The full 43-amino acid protein that TB-500 is derived from. Naturally occurring in most human tissues, TB-4 has a shorter half-life (~2 hours) compared to its synthetic fragment TB-500 (~2-4 days). Often mislabeled as 'TB-500' by vendors in premixed products.

Dosing Guidelines

Common Dose

2.5-5 mg 2-3x weekly

Frequency

2-3x weekly

Dose Range

1-10 mg per week

Note: Full 43-amino acid protein (not TB-500 fragment). Similar uses but shorter half-life. Often confused with TB-500 in marketplace.

Administration Method

Subcutaneous injection, topical for eye conditions

Best Time to Take

Morning or split doses

Due to short ~2 hour half-life, some protocols use multiple daily doses. Timing is flexible but consistency is important.

Protocol Duration

4-8 weeks typical protocol

Possible Side Effects

Not everyone experiences these. Individual responses vary.

  • Generally well-tolerated
  • Injection site reactions
  • Headache
  • Fatigue
  • May trigger histamine release - use caution with MCAS or histamine sensitivity

Frequently Asked Questions

What is the recommended dose for Thymosin Beta-4?

2.5-5 mg 2-3x weekly

How do you administer Thymosin Beta-4?

Subcutaneous injection, topical for eye conditions

When is the best time to take Thymosin Beta-4?

Morning or split doses

How long should you use Thymosin Beta-4?

4-8 weeks typical protocol

This information is for educational purposes only. Always consult with a healthcare professional before using any peptide. Dosing information is based on research literature and community reports, not medical advice.