How to Use Tesamorelin
Complete guide to Tesamorelin dosing, administration, timing, and protocol recommendations.
Quick Overview
An FDA-approved GHRH analog used to reduce excess abdominal fat in HIV-infected patients with lipodystrophy. New F8 formulation (Egrifta WR) approved March 2025 allows weekly reconstitution vs daily.
Dosing Guidelines
Common Dose
2 mg daily (F8: 1.28 mg daily)
Frequency
Once daily
Dose Range
1.28-2 mg daily
Note: FDA-approved dose is 2 mg (original) or 1.28 mg (F8/Egrifta WR formulation). Inject subcutaneously in abdomen. F8 requires weekly reconstitution vs daily.
Administration Method
Subcutaneous injection
Best Time to Take
Before bed (fasted)
FDA-approved GHRH analog works best on empty stomach, timed with natural GH release during sleep.
Protocol Duration
Indefinite for approved indication
Possible Side Effects
Not everyone experiences these. Individual responses vary.
- •Injection site reactions (common)
- •Joint pain
- •Peripheral edema
- •Pain in extremities
- •Muscle pain
Frequently Asked Questions
What is the recommended dose for Tesamorelin?
2 mg daily (F8: 1.28 mg daily)
How do you administer Tesamorelin?
Subcutaneous injection
When is the best time to take Tesamorelin?
Before bed (fasted)
How long should you use Tesamorelin?
Indefinite for approved indication
This information is for educational purposes only. Always consult with a healthcare professional before using any peptide. Dosing information is based on research literature and community reports, not medical advice.