How to Use Octreotide
Complete guide to Octreotide dosing, administration, timing, and protocol recommendations.
Quick Overview
Octreotide is a synthetic eight-amino-acid mimic of the natural hormone somatostatin, the body's main 'off switch' for hormone secretion. It shuts down excess growth hormone, so it is a frontline FDA-approved drug for acromegaly, and it also tames the flushing and diarrhea of hormone-secreting carcinoid and other neuroendocrine tumors. This is real, approved medicine with decades of clinical data behind it, sold as Sandostatin (injectable, since 1988), Sandostatin LAR (monthly depot), and Mycapssa (oral capsule, approved 2020).
Dosing Guidelines
Common Dose
100-500 mcg SC 2-3x daily or LAR monthly
Frequency
2-3x daily (SC) or monthly (LAR)
Dose Range
50-1500 mcg daily (SC)
Note: Somatostatin analog. Multiple indications including acromegaly and carcinoid tumors.
Administration Method
Subcutaneous or intramuscular depot
Best Time to Take
Morning or as directed
Timing may vary based on individual response and goals. Consistency is generally more important than specific timing.
Protocol Duration
Long-term / chronic use
Possible Side Effects
Not everyone experiences these. Individual responses vary.
- •Nausea
- •Diarrhea
- •Abdominal pain
- •Gallstones (52-63% long-term)
- •Bradycardia
Frequently Asked Questions
What is the recommended dose for Octreotide?
100-500 mcg SC 2-3x daily or LAR monthly
How do you administer Octreotide?
Subcutaneous or intramuscular depot
When is the best time to take Octreotide?
Morning or as directed
How long should you use Octreotide?
Long-term / chronic use
This information is for educational purposes only. Always consult with a healthcare professional before using any peptide. Dosing information is based on research literature and community reports, not medical advice.