How to Use HCG (Human Chorionic Gonadotropin)
Complete guide to HCG (Human Chorionic Gonadotropin) dosing, administration, timing, and protocol recommendations.
Quick Overview
HCG is a hormone produced in pregnancy that happens to be an almost perfect mimic of luteinizing hormone. That single fact is why it has two completely unrelated uses: it is an approved fertility medicine, and it is the standard tool for keeping the testicles working during testosterone therapy. It is also the basis of the discredited HCG diet, which is a separate story and not supported by evidence.
Dosing Guidelines
Common Dose
250-500 IU, 2-3x weekly (TRT adjunct)
Frequency
Two to three times weekly
Dose Range
250-10,000 IU depending entirely on purpose. TRT adjunct sits at the very bottom of that range, ovulation triggers at the top.
Note: Higher is not better here. Excessive HCG raises estrogen through aromatization of the testosterone it stimulates, and sustained very high doses can desensitize the Leydig cells you are trying to protect. It does not cause weight loss.
Administration Method
Subcutaneous or intramuscular injection. Reconstituted product needs refrigeration and is typically used within 30-60 days.
Best Time to Take
Consistent time of day, spaced evenly across the week
The long half-life means even spacing matters more than time of day. Consistency keeps testicular stimulation steady.
Protocol Duration
Ongoing alongside TRT. Fertility protocols run for a defined course.
Possible Side Effects
Not everyone experiences these. Individual responses vary.
- •Injection site reactions
- •Fluid retention
- •Gynecomastia risk, since stimulated testicular testosterone can aromatize to estrogen
- •Mood changes
- •Acne
Frequently Asked Questions
What is the recommended dose for HCG (Human Chorionic Gonadotropin)?
250-500 IU, 2-3x weekly (TRT adjunct)
How do you administer HCG (Human Chorionic Gonadotropin)?
Subcutaneous or intramuscular injection. Reconstituted product needs refrigeration and is typically used within 30-60 days.
When is the best time to take HCG (Human Chorionic Gonadotropin)?
Consistent time of day, spaced evenly across the week
How long should you use HCG (Human Chorionic Gonadotropin)?
Ongoing alongside TRT. Fertility protocols run for a defined course.
This information is for educational purposes only. Always consult with a healthcare professional before using any peptide. Dosing information is based on research literature and community reports, not medical advice.