How to Use Cagrilintide

Complete guide to Cagrilintide dosing, administration, timing, and protocol recommendations.

Quick Overview

A long-acting amylin analog developed by Novo Nordisk for obesity treatment. Works through a different mechanism than GLP-1 agonists, targeting amylin receptors in the brain to reduce appetite and slow gastric emptying. Shows enhanced weight loss when combined with semaglutide (CagriSema).

Dosing Guidelines

Common Dose

2.4 mg weekly

Frequency

Once weekly

Dose Range

1.0-2.4 mg weekly (dose escalation)

Note: Most effective when combined with semaglutide (CagriSema). Works through amylin pathway which is complementary to GLP-1 mechanism. Dose escalation typically used to minimize GI side effects. Not yet commercially available - still in clinical trials.

Administration Method

Subcutaneous injection once weekly

Best Time to Take

Any consistent time weekly

Once-weekly injection provides sustained amylin receptor activation. Timing is flexible but should be consistent week to week.

Protocol Duration

Long-term / chronic use expected

Possible Side Effects

Not everyone experiences these. Individual responses vary.

  • Nausea (common, usually transient)
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal pain

Frequently Asked Questions

What is the recommended dose for Cagrilintide?

2.4 mg weekly

How do you administer Cagrilintide?

Subcutaneous injection once weekly

When is the best time to take Cagrilintide?

Any consistent time weekly

How long should you use Cagrilintide?

Long-term / chronic use expected

This information is for educational purposes only. Always consult with a healthcare professional before using any peptide. Dosing information is based on research literature and community reports, not medical advice.