Peptide Combinations

Popular Stacks & Synergies

Discover proven peptide combinations, popular pre-made blends, and learn which peptides work best together.

Popular Pre-Made Blends

Vendor-formulated combinations with proven synergies

Synergistic Combinations

Peptides that work better together than alone

GH Optimization

CJC-1295Ipamorelin

The gold standard for growth hormone release. CJC-1295 provides sustained GH signaling while Ipamorelin triggers clean GH pulses without cortisol spikes.

Benefit: Enhanced muscle growth, fat loss, sleep quality, and recovery

Cognitive Enhancement

SemaxSelank

Synergistic nootropics - Semax boosts BDNF and focus while Selank reduces anxiety and supports mood. Together they enhance mental performance.

Benefit: Improved focus, memory, reduced anxiety, neuroprotection

Deep Sleep & Recovery

DSIPIpamorelin

DSIP promotes deep delta-wave sleep while Ipamorelin's GH release peaks during sleep, maximizing overnight recovery.

Benefit: Better sleep quality, enhanced overnight recovery, mood improvement

Complete Healing

BPC-157TB-500GHK-Cu

Triple-action healing combining local repair (BPC-157), systemic recovery (TB-500), and collagen production (GHK-Cu).

Benefit: Accelerated injury healing, tissue regeneration, scar reduction

Metabolic Optimization

Tesamorelin5-Amino-1MQ

Tesamorelin reduces visceral fat while 5-Amino-1MQ enhances cellular metabolism through NNMT inhibition.

Benefit: Fat loss, improved body composition, metabolic health

Combinations to Avoid

Peptides that may have negative interactions or redundant effects

Multiple GH Secretagogues

Caution

Example: CJC-1295 + GHRP-6 + MK-677 + Ipamorelin (all at once)

Excessive GH stimulation can cause side effects like water retention, joint pain, and potential insulin resistance. Stick to one GHRH + one GHRP.

Melanotan I + Melanotan II

Caution

Example: MT-1 + MT-2 together

Both stimulate melanocortin receptors. Using together provides no additional benefit and increases side effect risk.

Multiple Weight Loss Peptides

Avoid

Example: Semaglutide + Tirzepatide + AOD-9604

Stacking GLP-1 agonists dramatically increases nausea and GI side effects. Choose one primary weight loss peptide.

Stimulating Peptides at Night

Note

Example: Semax, ACTH fragments before bed

Stimulating nootropics can interfere with sleep onset and quality. Use in morning or early afternoon only.

Build Your Own Stack

Use our interactive Stack Builder to create custom peptide combinations with synergy analysis, timing recommendations, and exportable protocols.

Open Stack Builder

Educational Information Only

This information is provided for educational purposes only and is not intended as medical advice. Always consult with qualified healthcare providers before making any health-related decisions.